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Animal models demonstrate increased antioxidant biomarkers and reduced lipid peroxidation after GHK-Cu treatment

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10.1038/s41586-020-2247-3 Nature 87 MontagneA.NikolakopoulouA

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While the PARS1 inhibitor halofuginone exhibited toxicity, its optimized derivative DWN12088 demonstrated improved safety and efficacy in preclinical models and is currently under clinical investigation for IPF [143]

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